Samiksha Jaiswal (Editor)

Cinnamyl alcohol dehydrogenase

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EC number
  
1.1.1.195

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
55467-36-2

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) is an enzyme that catalyzes the chemical reaction

cinnamyl alcohol + NADP+ cinnamaldehyde + NADPH + H+

Thus, the two substrates of this enzyme are cinnamyl alcohol and NADP+, whereas its 3 products are cinnamaldehyde, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cinnamyl-alcohol:NADP+ oxidoreductase. Other names in common use include cinnamyl alcohol dehydrogenase, and CAD. This enzyme participates in phenylpropanoid biosynthesis.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1YQD, 1YQX, 2CF5, and 2CF6.

References

Cinnamyl-alcohol dehydrogenase Wikipedia


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