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Chrysophanic acid

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Chrysophanic acid fileselleckchemcomdownloadsstructChrysophanic

Chrysophanic acid, also known as chrysophanol, is a fungal isolate and a natural anthraquinone. It blocks the proliferation of colon cancer cells in vitro.

Mechanism of action

Chrysophanol induces the necrosis of cancer cells via a reduction in ATP levels. Chrysophanol attentuates the effects of lead exposure in mice by reducing hippocampal neuronal cytoplasmic edema, enhancing mitochondrial crista fusion, significantly increasing memory and learning abilities, reducing lead content in blood, heart, brain, spleen, kidney and liver, promoting superoxide dismutase and glutathione peroxidase activities and reducing malondialdehyde level in the brain, kidney and liver.

References

Chrysophanic acid Wikipedia