Neha Patil (Editor)

Cholesterol 5,6 oxide hydrolase

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EC number
  
3.3.2.11

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

Cholesterol-5,6-oxide hydrolase (EC 3.3.2.11, cholesterol-epoxide hydrolase, ChEH) is an enzyme with systematic name 5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase. This enzyme catalyses the following chemical reaction

(1) 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O ⇌ 5alpha-cholestane-3beta,5alpha,6beta-triol (2) 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O ⇌ 5alpha-cholestane-3beta,5alpha,6beta-triol

The enzyme works equally well with either epoxide as substrate.

References

Cholesterol-5,6-oxide hydrolase Wikipedia
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