Trade names Parafonforte MedlinePlus a682577 ATC code M03BB03 (WHO) CAS ID 95-25-0 | AHFS/Drugs.com Monograph Routes of
administration oral Bioavailability well absorbed Molar mass 169.565 g/mol | |
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Chlorzoxazone (INN) is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes. It is sold under the trade names "Lorzone", Paraflex and Muscol and in combination form as Parafon Forte, a combination of chlorzoxazone and acetaminophen (paracetamol). Possible side effects include dizziness, lightheadedness, malaise, nausea, vomiting, and liver dysfunction. Used with acetaminophen it has added risk of hepatoxicity, which is why the combination is not recommended. It can also be administered for acute pain in general and for tension headache (muscle contraction headache).
As of 2015 the cost for a typical course of medication in the United States is less than 25 USD.