EC number 1.1.1.225 ExPASy NiceZyme view | CAS number 102484-73-1 | |
In enzymology, a chlordecone reductase (EC 1.1.1.225) is an enzyme that catalyzes the chemical reaction
chlordecone alcohol + NADP+
Thus, the two substrates of this enzyme are chlordecone alcohol and NADP+, whereas its 3 products are chlordecone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is chlordecone-alcohol:NADP+ 2-oxidoreductase. This enzyme is also called CDR.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2FVL.
References
Chlordecone reductase Wikipedia(Text) CC BY-SA