Chiles is a surname. Notable people with the surname include:
Adrian Chiles (born 1967), British TV and radio presenter
Eddie Chiles (1910–1993), American businessman
Henry G. Chiles, Jr. (born 1938), retired United States Navy four star admiral
James Chiles (politician) (1802-1883), Missouri State Senator, granduncle of Harry S. Truman
James Chiles (died 1873), Confederate outlaw who rode with William Quantrill's gang, son of Senator Chiles and uncle of President Truman
John Chiles (born 1988), American born wide receiver playing in the Canadian Football League.
Colonel Joseph Chiles, (1810–1885), an early California pioneer and guide
Lawton Chiles (1930–1998), American politician
Linden Chiles (1933–2013), American actor
Lois Chiles (born 1947), American actress and model
Marcellus H. Chiles (1895–1918), American soldier, World War I Medal of Honor recipient
Pearce Chiles (1899–?), American baseball player
Rich Chiles (born 1949), former Major League Baseball outfielder
Walter Chiles (died 1653), Virginia colonial politician
Cassandra Chiles (born 1972), American musician
Fictional characters:
Jackie Chiles, fictional attorney on the American television series Seinfeld
