In the treatment of cancer, chemoprotective agents are drugs which protect healthy tissue from the toxic effects of anticancer drugs.
Examples include:
Amifostine, approved by the FDA in 1995, which helps prevent kidney damage in patients undergoing cisplatin and carboplatin chemotherapy
Mesna, approved by the FDA in 1988, which helps prevent hemorrhagic cystitis (bladder bleeding) in patients undergoing cyclophosphamide or ifosfamide chemotherapy
Dexrazoxane, approved by the FDA in 1995, which helps prevent heart problems in patients undergoing doxorubicin chemotherapy
