Chappuis /ˈtʃæpiəs/ is a surname. Notable people with the surname include:
Robert "Bob" Richard Chappuis (1923–2012), American football player
Charyl Chappuis, Swiss-Thai footballer
Eduardo Dibós Chappuis (called "Chachi"), Peruvian politician
Eliane Cat-Tuong Chappuis (born 1978), model, actress, singer, producer of Swiss descent
Friedrich-Wilhelm von Chappuis (1886–1942), General der Infanterie
James Chappuis (1854–1934), French chemist
Jason Lamy-Chappuis (born 1986, Missoula, Montana, USA), Franco-American ski jumper and cross-country skier
Liliane Chappuis (1955–2007), Swiss politician
Marie de Sales Chappuis, aka Marie-Thérèse Chappuis
Paul Emile Chappuis (1816–1887), photographer, an inventor and manufacturer
Philippe Chappuis (born 1967)
Bertil Chappuis(1966)
Chappuis bands: absorption bands in the ozone layer
