Chamberlin is a surname. Notable people with the surname include:
Ann Chamberlin, American novelist
Beth Chamberlin (born 1963), American television actress
Clarence Chamberlin (1893-1976), American aviator
Donald D. Chamberlin (born 1944), American computer scientist, co-designer of the SQL database language
Edson Joseph Chamberlin (1852-1924), president of the Grand Trunk Railway
Edward Chamberlin (1899-1967), American economist
Frank Chamberlin (1978–2013), American football player
Guy Chamberlin (1894–1967), American football player
Harry Chamberlin (1887-1944), Olympic equestrian and US Army brigadier general
Harry Chamberlin, inventor of the Chamberlin musical keyboard instrument
Jan Rooney née Chamberlin, singer and widow of Mickey Rooney
Jim Chamberlin (1915-1981), Canadian aerodynamicist who worked on the Canadian Avro Arrow, NASA's Gemini spacecraft and the Apollo program
Jimmy Chamberlin (born 1964), American drummer of The Smashing Pumpkins
Joseph Conrad Chamberlin (1898–1962), American arachnologist
Kevin Chamberlin (born 1963), American actor
Lee Chamberlin (1938–2014), American actress
Mason Chamberlin (1727–1787), English portrait painter
Michael Chamberlin (disambiguation)
Paul Chamberlin (born 1962), American tennis player
Ralph Vary Chamberlin (1879–1967), American biologist and historian
G. Richard Chamberlin (born 1946), American politician from Georgia
Thomas Chrowder Chamberlin (1843–1928), American geologist
Willard Joseph Chamberlin (1890–1971), American entomologist and World War I pilot
William Henry Chamberlin (1897–1969), American historian and journalist
William Henry Chamberlin (philosopher) (1870-1921), Mormon philosopher and theologian