Chaffee is a surname. Notable people with the surname include:
Adna Chaffee (1842–1914), American general
Adna R. Chaffee, Jr. (1884–1941), American general, son of Adna Chaffee
Calvin C. Chaffee (1811–1896), American doctor, politician, and abolitionist
Emory Leon Chaffee (1885–1975), American physicist and engineer
Jerome B. Chaffee (1825–1886), American entrepreneur and senator from Colorado
John Chafee (1922–1999), American politician and Secretary of the Navy
Lincoln Chafee (born 1953), Rhode Island governor and former U.S. Senator; son of John Chafee
Roger B. Chaffee (1935–1967), American Apollo astronaut
Suzy Chaffee (born 1946), American Olympic skier and actress
Zechariah Chafee (1885–1957), free speech and legal scholar
Fictional characters:
Alan Chaffee, fictional character in Village of the Damned (1995 film)
