| Espadarana prosoblepon, Centrolene ilex, Nymphargus grandisonae, Centrolene quindianum, Andes giant glass frog|
Centrolene is a genus of glass frogs in the family Centrolenidae. The adult males are characterized by having a humeral spine, as most members of this family. The delimitation of this genus versus Cochranella is not fully resolved, and some species formerly in Centrolenella — which is nowadays synonymized with Centrolene — are now in Hyalinobatrachium.
The genus is known as "giant glass frogs". But this is merely relative to the rest of their family, which contains numerous extremely diminutive species.
As of 2015, the genus contains 27 species: