Trade names Zinnat, Ceftin, Ceftum Legal status US: ℞-only Excretion Urine | Routes of
administration Oral Bioavailability well absorbed | |
 | ||
Metabolism | ||
Cefuroxime axetil is a second generation oral cephalosporin antibiotic. It was discovered by Glaxo now GlaxoSmithKline and introduced in 1987 as Zinnat. It was approved by FDA on Dec 28, 1987. It is available by GSK as Ceftin in US and Ceftum in India.
It is an acetoxyethyl ester prodrug of cefuroxime which is effective orally. The activity depends on in vivo hydrolysis and release of cefuroxime tablets.
References
Cefuroxime axetil Wikipedia(Text) CC BY-SA