CAS Number 80370-57-6 ChemSpider 4886668 Molar mass 523.56 g/mol | PubChem CID 6328657 UNII 83JL932I1C | |
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AHFS/Drugs.com International Drug Names ATCvet code QJ01DD90 (WHO) QJ51DD90 (WHO) |
Ceftiofur is an antibiotic of the cephalosporin type (third generation), licensed for use in veterinary medicine. It was first described in 1987. It is marketed by pharmaceutical company Zoetis as Excenel, Naxcel, and Excede and is also the active ingredient in that company's Spectramast LC (lactating cow formulation) and Spectramast DC (dry cow formulation) product.

It is resistant to the antibiotic resistance enzyme beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported.

The metabolite desfurolyceftiofur also has antibiotic activity. The two compounds are measured together to measure for antibiotic activity in milk (alongside other antibiotics).


References
Ceftiofur Wikipedia(Text) CC BY-SA