Girish Mahajan (Editor)

Cefacetrile

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Protein binding
  
23 to 38%

Molar mass
  
339.325 g/mol

Cefacetrile

Trade names
  
Celospor, Celtol, Cristacef

AHFS/Drugs.com
  
International Drug Names

Routes of administration
  
Intravenous, intramuscular, intramammary

ATC code
  
J01DB10 (WHO) QJ51DB10 (WHO)

Legal status
  
In general: ℞ (Prescription only)

Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in gram-positive and gram-negative bacterial infections. It is a bacteriostatic antibiotic. Cefacetrile is marketed under the trade names Celospor, Celtol, and Cristacef, and as Vetimast for the treatment of mammary infections in lactating cows.

Synthesis

It was made by reacting 7-ACA (7-aminocephalosporanic acid) with cyanoacetyl chloride in the presence of tributylamine.

References

Cefacetrile Wikipedia