Species Human Entrez 1515 | Human Mouse Ensembl ENSG00000136943 | |
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Aliases CTSV, cathepsin V, CATL2, CTSL2, CTSU External IDs MGI: 88564 HomoloGene: 76699 GeneCards: CTSV | ||
Cathepsin L2, also known as cathepsin V and encoded by the CTSL2 gene, is a human gene.
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes.
Clinical significance
Cathepsin L2 may play a role in the pathogenesis of keratoconus.
References
Cathepsin L2 Wikipedia(Text) CC BY-SA