Caskey is a surname. Notable people with the surname include:
Alex Caskey (born 1988), American soccer player
Billy Caskey (born 1954), Northern Ireland footballer
C. Thomas Caskey, American physician and geneticist
Craig Caskey (born 1949), American baseball player
Darren Caskey (born 1974), English footballer
Elizabeth Caskey (1910-1994), Classical scholar
John Caskey (1908–1981), American archaeologist and classical scholar
Lafayette Caskey (1824-1881), American politician and carpenter
Caskey (rapper), American rapper signed
