The twenty-second season of the Case Closed anime was directed by Yasuichiro Yamamoto and produced by TMS Entertainment and Yomiuri Telecasting Corporation. The series is based on Gosho Aoyama's Case Closed manga series. In Japan, the series is titled Detective Conan (名探偵コナン, Meitantei Conan) but was changed due to legal issues with the title Detective Conan. The series focuses on the adventures of teenage detective Shinichi Kudo who was turned into a child by a poison called APTX 4869, but continues working as a detective under the alias Conan Edogawa.
The episodes use five pieces of theme music: two opening and three ending themes. The first opening theme is "Try Again" by Mai Kuraki starting from episode 681 to 695. The second opening theme is "Q&A" by B'z starting from episode 696. The first ending theme is Koi ni Koi Shite (恋に恋して?, lit. "In Love With Love") by Mai Kuraki and is used up to episode 685. The second ending theme is Hitomi no Melody (瞳のメロディ?, lit. "Melody of Eyes") by Boyfriend from episode 686 to 704. The third ending theme is Kimi no Egao ga Nani Yori mo Sukidatta (君の笑顔がなによりも好きだった?, lit."I Loved Your Smile More Than Anything Else") by Chicago Poodle starting from episode 705.