Harman Patil (Editor)

Carnitine O octanoyltransferase

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EC number
  
2.3.1.137

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
39369-19-2

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a carnitine O-octanoyltransferase (EC 2.3.1.137) is an enzyme that catalyzes the chemical reaction

octanoyl-CoA + L-carnitine CoA + L-octanoylcarnitine

Thus, the two substrates of this enzyme are octanoyl-CoA and L-carnitine, whereas its two products are CoA and L-octanoylcarnitine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is octanoyl-CoA:L-carnitine O-octanoyltransferase. Other names in common use include medium-chain/long-chain carnitine acyltransferase, carnitine medium-chain acyltransferase, easily solubilized mitochondrial carnitine palmitoyltransferase, and overt mitochondrial carnitine palmitoyltransferase.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1XL7, 1XL8, 1XMC, and 1XMD.

References

Carnitine O-octanoyltransferase Wikipedia