Carbazole 1,9a dioxygenase

Updated on Dec 17, 2024

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EC number 1.14.12.22 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Carbazole 1,9a-dioxygenase (EC 1.14.12.22, CARDO) is an enzyme with systematic name 9H-carbazole,NAD(P)H:oxygen oxidoreductase (2,3-hydroxylating). This enzyme catalyses the following chemical reaction

9H-carbazole + NAD(P)H + H⁺ + O₂ ⇌ 2'-aminobiphenyl-2,3-diol + NAD(P)⁺

Carbazole 1,9a-dioxygenase catalyses the first reaction in the pathway of carbazole degradation.

References

Carbazole 1,9a-dioxygenase Wikipedia

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