Capuano is an Italian surname referring to the Italian city of Capua. Notable people with the surname include:
Antonio Capuano (actor) (died 1963), Argentine actorBarry Capuano (born 1940), Australian-rules footballerCara Capuano, American sportscasterChris Capuano (born 1978), American baseball pitcherCiro Capuano (born 1981), Italian footballerDave Capuano (born 1968), American ice hockey playerDomenico Capuano (born 1975), Italian music producer and composerEzio Capuano, (born 1965), Italian football coachFrancesco Capuano Di Manfredonia, 15th-century Italian astronomerJack Capuano (born 1966), American ice hockey player and coachLuigi Capuano (born 1904), Italian film director and screenwriterMarco Capuano (born 1991), Italian footballerMatthew Capuano (born 1975), Australian-rules footballerMike Capuano (born 1952), American politician, currently a congressman from MassachusettsPeter of Capua (died 1214), Italian theologian, philosopher, and churchman, sometimes called Peter CapuanoRico (artist), Scottish musician born Rico Capuano