Cahoon is a surname. Notable people with the surname include:
Ben Cahoon (born 1972), football player in the CFL
Frank Kell Cahoon (1934–2013), American businessman and politician
Kevin Cahoon, American actor/singer/songwriter
Lauren Cahoon (born 1985), Taekwondo martial artist
Martha Cahoon (1905 - 1999), American artist
Ralph Cahoon (1910 - 1982), artist and furniture decorator
Reynolds Cahoon (1790-1861), Latter-day Saint builder of Kirtland Temple
Tiny Cahoon (1900 - 1973), American football player
Todd Cahoon (born 1973), American actor
William Cahoon (1774 - 1833), United States politician from Vermont