Suvarna Garge (Editor)

Caffeine synthase

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EC number
  
2.1.1.160

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
155215-94-4

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Caffeine synthase is a methyltransferase enzyme involved in the caffeine biosynthesis pathway. It is expressed in tea species, coffee species, and cocoa species. The enzyme catalyses the following reactions:

  • S-adenosyl-L-methionine + theobromine ⇌ S-adenosyl-L-homocysteine + caffeine + H+
  • S-adenosyl-L-methionine + paraxanthine ⇌ S-adenosyl-L-homocysteine + caffeine + H+
  • 7-methylxanthine + S-adenosyl-L-methionine ⇌ S-adenosyl-L-homocysteine + H+ + theobromine

    • Caffeine synthase is expressed in the Camellia species irrawadiensis, ptilophylla, and sinensis; the Coffea species arabica, and canephora; and in Theobroma cacao.

    References

    Caffeine synthase Wikipedia
    (Text) CC BY-SA


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