Cadena is a surname. Notable people with the surname include:
Ana Lilia Garza Cadena (born 1970), Mexican politician affiliated with the PVEMCarlos Cadena (1917–2001), Mexican American lawyer, civil rights activist and judge based in San Antonio, TexasDaniel Cadena (born 1987), football forwardDez Cadena (born 1961), American punk rock singer and guitaristFrancisco Páez de la Cadena (born 1951), Spanish garden historianFreddy Cadena (born 1963), Ecuadorian orchestra conductor, a resident of RussiaJosé Torres Cadena (born 1952), former football (soccer) referee from ColombiaJulio César Cadena (born 1963), former Colombian racing cyclistMariano Velazquez de la Cadena (1778–1860), accomplished Mexican American grammarian, scholar, and authorOzzie Cadena (1924–2008), American record producer with Savoy Records and Prestige Records who recorded gospel and jazz musicRicardo Cadena (born 1969), retired professional footballer from MexicoRodolfo Cadena (1943–1972), Mexican-American mob boss and legendary figure in the Mexican Mafia prison gangRodrigo de la Cadena (born 1988), Mexican singer, performer, songwriter, radio host, and musicianTony Cadena (born 1963), accomplished punk rock singer/songwriter and poetCarlos Cadena Gaitan (born 1983), journalist and affiliated researcher with the United Nations UniversityManuel Cadena Morales (born 1948), Mexican politician from the Institutional Revolutionary Party