Species Human Entrez 54360 | Human Mouse Ensembl ENSG00000170891 | |
Aliases CYTL1, C17, C4orf4, cytokine like 1 External IDs MGI: 2684993 HomoloGene: 10254 GeneCards: CYTL1 | ||
Cytokine-like 1 is a protein that in humans is encoded by the CYTL1 gene.
Function
C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 (MIM 142230) surface marker. Functionally, C17 was identified as a secretory protein expressed in CD34+ haemopoietic cells CYTL1 seems to regulate chondrogenesis and is required for the maintenance of cartilage homeostasis and might, additionally, work as a regulatory factor in embryo implantation in the stage of early pregnancy.
This family of proteins, C17, is found in vertebrates. Proteins have two conserved sequence motifs: PPTCYSR and DDC.
References
CYTL1 Wikipedia(Text) CC BY-SA