Species Human Entrez 8804 | Human Mouse Ensembl ENSG00000143162 | |
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Aliases CREG1, CREG, cellular repressor of E1A stimulated genes 1 External IDs MGI: 1344382 HomoloGene: 31199 GeneCards: CREG1 | ||
Protein CREG1 is a protein that in humans is encoded by the CREG1 gene.
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
References
CREG1 Wikipedia(Text) CC BY-SA