Species Human Entrez 8533 | Human Mouse Ensembl ENSG00000141030 | |
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Aliases COPS3, CSN3, SGN3, COP9 signalosome subunit 3 External IDs MGI: 1349409 HomoloGene: 2710 GeneCards: COPS3 | ||
COP9 signalosome complex subunit 3 is a protein that in humans is encoded by the COPS3 gene. It encodes a subunit of the COP9 signalosome.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I-kappa-B-alpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
References
COP9 signalosome complex subunit 3 Wikipedia(Text) CC BY-SA