Entrez 25932 | Ensembl ENSG00000169504 | |
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Aliases CLIC4, CLIC4L, H1, MTCLIC, huH1, p64H1, chloride intracellular channel 4 External IDs MGI: 1352754 HomoloGene: 8490 GeneCards: CLIC4 |
Chloride intracellular channel 4, also known as CLIC4, is a eukaryotic gene.
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Binding partners
CLIC4 binds to dynamin I, α-tubulin, β-actin, creatine kinase and two 14-3-3 isoforms.
References
CLIC4 Wikipedia(Text) CC BY-SA