Girish Mahajan (Editor)

CLCNKB

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Species
  
Entrez
  
1188

Human
  
Ensembl
  
ENSG00000184908

CLCNKB

Aliases
  
CLCNKB, CLCKB, ClC-K2, ClC-Kb, chloride voltage-gated channel Kb

External IDs
  
MGI: 1329026 HomoloGene: 65 GeneCards: CLCNKB

Chloride channel Kb, also known as CLCNKB, is a protein which in humans is encoded by the CLCNKB gene.

Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

References

CLCNKB Wikipedia


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