Species Human Entrez 1184 | Human Mouse Ensembl ENSG00000171365 | |
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Aliases CLCN5, CLC5, CLCK2, ClC-5, DENTS, NPHL1, NPHL2, XLRH, XRN, hCIC-K2, chloride voltage-gated channel 5 External IDs MGI: 99486 HomoloGene: 73872 GeneCards: CLCN5 | ||
H(+)/Cl(-) exchange transporter 5 is a protein that in humans is encoded by the CLCN5 gene.
This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent's Disease and renal tubular disorders complicated by nephrolithiasis. Although a member of a family of chloride channels, the CLCN5 protein allows movement of protons in the opposite direction of Cl(-), thus functioning as an antiporter.
References
CLCN5 Wikipedia(Text) CC BY-SA