Entrez 1134 | Ensembl ENSG00000138435 | |
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Aliases CHRNA1, ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS, CMS1A, CMS1B, Cholinergic receptor, nicotinic, alpha 1, cholinergic receptor nicotinic alpha 1 subunit External IDs MGI: 87885 HomoloGene: 59 GeneCards: CHRNA1 | ||
Neuronal acetylcholine receptor subunit alpha-1, also known as nAChRα1, is a protein that in humans is encoded by the CHRNA1 gene. The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR).
The muscle acetylcholine receptor consists of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.
Interactions
Cholinergic receptor, nicotinic, alpha 1 has been shown to interact with CHRND.
References
CHRNA1 Wikipedia(Text) CC BY-SA