Species Human Entrez 51510 | Human Mouse Ensembl ENSG00000086065 | |
 | ||
Aliases CHMP5, C9orf83, HSPC177, PNAS-2, SNF7DC2, Vps60, CGI-34, charged multivesicular body protein 5 External IDs MGI: 1924209 HomoloGene: 5757 GeneCards: CHMP5 | ||
Charged multivesicular body protein 5 is a protein that in humans is encoded by the CHMP5 gene.
Function
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
References
CHMP5 Wikipedia(Text) CC BY-SA