Harman Patil (Editor)

CHD1L

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Species
  
Human

Entrez
  
9557

Human
  
Mouse

Ensembl
  
ENSG00000131778

CHD1L

Aliases
  
CHD1L, ALC1, CHDL, chromodomain helicase DNA binding protein 1-like, chromodomain helicase DNA binding protein 1 like

External IDs
  
MGI: 1915308 HomoloGene: 11590 GeneCards: CHD1L

Chromodomain-helicase-DNA-binding protein 1-like is an enzyme that in humans is encoded by the CHD1L gene. It has been implicated in chromatin remodeling and DNA relaxation process required for DNA replication, repair and transcription.

  • 1q21.1 deletion syndrome
  • 1q21.1 duplication syndrome
  • With 1q21.1 deletion syndrome a disturbance occurs, which leads to increased DNA breaks. The role of CHD1L is similar to that of helicase with the Werner syndrome

    References

    CHD1L Wikipedia