Species Human Entrez 64411 | Human Mouse Ensembl ENSG00000120318 | |
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Aliases ARAP3, CENTD3, DRAG1, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 External IDs MGI: 2147274 HomoloGene: 11199 GeneCards: ARAP3 | ||
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 is a protein that in humans is encoded by the ARAP3 gene.
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its full-length nature has not been determined.
References
CENTD3 Wikipedia(Text) CC BY-SA