Harman Patil (Editor)

CEACAM3

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Species
  
Entrez
  
1084

Human
  
Ensembl
  
ENSG00000170956

CEACAM3

Aliases
  
CEACAM3, CD66D, CEA, CGM1, W264, W282, carcinoembryonic antigen related cell adhesion molecule 3

External IDs
  
HomoloGene: 130497 GeneCards: CEACAM3

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d (Cluster of Differentiation 66d), is a human gene.

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Use

CEACAM3 is expressed exclusively on granulocytes and used as granulocyte marker.

References

CEACAM3 Wikipedia


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