Entrez 995 | Ensembl ENSG00000158402 | |
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Aliases CDC25C, CDC25, PPP1R60, cell division cycle 25C External IDs MGI: 88350 HomoloGene: 1356 GeneCards: CDC25C |
M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene.
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
References
CDC25C Wikipedia(Text) CC BY-SA