Puneet Varma (Editor)

CDC14A

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Species
  
Entrez
  
8556

Human
  
Ensembl
  
ENSG00000079335

CDC14A

Aliases
  
CDC14A, cdc14, hCDC14, cell division cycle 14A, DFNB105

External IDs
  
MGI: 2442676 HomoloGene: 75343 GeneCards: CDC14A

Dual specificity protein phosphatase CDC14A is an enzyme that in humans is encoded by the CDC14A gene.

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Interactions

CDC14A has been shown to interact with P53.

References

CDC14A Wikipedia


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