Species Human Entrez 3672 | Human Mouse Ensembl ENSG00000213949 | |
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Aliases ITGA1, CD49a, VLA1, integrin subunit alpha 1 External IDs OMIM: 192968 MGI: 96599 HomoloGene: 57137 GeneCards: ITGA1 | ||
CD49a is an integrin alpha subunit. It makes up half of the α1β1 integrin duplex.
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
References
CD49a Wikipedia(Text) CC BY-SA