Symbol TNFRSF1A Entrez 7132 OMIM 191190 | Alt. symbols CD120a, TNFR1 HUGO 11916 RefSeq NM_001065 | |
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CD120 (Cluster of Differentiation 120) can refer to two members of the tumor necrosis factor receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2).
Receptor subtypes
There are two variants of the receptor, each encoded by a separate gene:
TNFR1 is the receptor type responsible for mediation of TNF-alpha induced sickness behavior, and is involved in neurotoxic processes. Elevated levels of TNFR1 has been found in severe mental disorders.
References
CD120 Wikipedia(Text) CC BY-SA