Species Human Entrez 10576 | Human Mouse Ensembl ENSG00000166226 | |
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Aliases CCT2, 99D8.1, CCT-beta, CCTB, HEL-S-100n, PRO1633, TCP-1-beta, chaperonin containing TCP1 subunit 2 External IDs MGI: 107186 HomoloGene: 4696 GeneCards: CCT2 | ||
T-complex protein 1 subunit beta is a protein that in humans is encoded by the CCT2 gene.
Contents
Function
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.
Interactions
CCT2 (gene) has been shown to interact with PPP4C.
References
CCT2 (gene) Wikipedia(Text) CC BY-SA