EC number 4.4.1.13 Human Mouse | Species Human Entrez 883 | |
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Aliases KYAT1, GTK, KAT1, KATI, CCBL1, kynurenine aminotransferase 1 External IDs MGI: 1917516 HomoloGene: 37872 GeneCards: KYAT1 | ||
Kynurenine—oxoglutarate transaminase 1 is an enzyme that in humans is encoded by the CCBL1 gene.
This gene encodes a cytosolic enzyme which is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism leads to the formation of reactive metabolites which can lead to nephrotoxicity and neurotoxicity.
References
CCBL1 Wikipedia(Text) CC BY-SA