Entrez 23624 | Ensembl ENSG00000142273 | |
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Aliases CBLC, CBL-3, CBL-SL, RNF57, Cbl proto-oncogene C External IDs MGI: 1931457 HomoloGene: 8108 GeneCards: CBLC | ||
Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene.
CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling (Keane et al., 1999).[supplied by OMIM]
Interactions
CBLC has been shown to interact with FYN and Epidermal growth factor receptor.
References
CBLC Wikipedia(Text) CC BY-SA