Rahul Sharma (Editor)

CACNA2D2

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Species
  
Entrez
  
9254

Human
  
Ensembl
  
ENSG00000007402

CACNA2D2

Aliases
  
CACNA2D2, CACNA2D, calcium voltage-gated channel auxiliary subunit alpha2delta 2

External IDs
  
MGI: 1929813 HomoloGene: 4400 GeneCards: CACNA2D2

Voltage-dependent calcium channel subunit alpha2delta-2 is a protein that in humans is encoded by the CACNA2D2 gene.

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

References

CACNA2D2 Wikipedia


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