Entrez 91768 | Ensembl ENSG00000134508 | |
Aliases CABLES1, CABL1, CABLES, HsT2563, IK3-1, Cdk5 and Abl enzyme substrate 1 External IDs MGI: 1927065 HomoloGene: 11097 GeneCards: CABLES1 | ||
CDK5 and ABL1 enzyme substrate 1 is a protein that in humans is encoded by the CABLES1 gene.
CABLES1 is a cyclin-dependent kinase (CDK)-binding protein that plays a role in proliferation and/or cell differentiation (Zukerberg et al., 2004).[supplied by OMIM]. It is a tumor suppressor gene which losing it (by mutations, knockout, knockdown or inactivation) may lead to colorectal cancer CRC.
References
CABLES1 Wikipedia(Text) CC BY-SA