Chromosome 9 open reading frame 156 is a protein that in humans is encoded by the C9orf156 gene. The gene is also known as NAP1 and HSPC219; the orthologue in mice is 5830415F09Rik.
Model organisms
Model organisms have been used in the study of C9orf156 function. A conditional knockout mouse line, called 5830415F09Riktm1a(EUCOMM)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the Wellcome Trust Sanger Institute.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty four tests were carried out on mutant mice, but no significant abnormalities were observed.