Species Human Entrez 56892 | Human Mouse Ensembl ENSG00000176907 | |
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Aliases C8orf4, TC-1, TC1, chromosome 8 open reading frame 4 External IDs MGI: 1916318 HomoloGene: 10590 GeneCards: C8orf4 | ||
Uncharacterized protein C8orf4 is a protein that in humans is encoded by the C8orf4 gene.
Function
This gene encodes a small, monomeric, predominantly unstructured protein (106 amino acids, 12.3 kDa, isoelectric point 9.39). It is a positive regulator of the Wnt / beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes.
References
C8orf4 Wikipedia(Text) CC BY-SA