ATC code R05DB13 (WHO) Excretion 90% renal PubChem CID 28892 Protein binding 98% | Biological half-life 6 hours CAS Number 18109-80-3 Molar mass 307.428 g/mol | |
 | ||
AHFS/Drugs.com International Drug Names | ||
Butamirate (or brospamin) is a cough suppressant.
A study found it to bind to the cough center in the medulla oblongata, more specifically the dextromethorphan-binding site in guinea pig brain with high affinity.
As a 2-(2-diethylaminoethoxy)ethyl ester, it is chemically related to oxeladin and pentoxyverine, which are in the same class. (Oxeladin has an additional ethyl group in its carboxylic acid, pentoxyverine has both ethyl groups of oxeladin replaced by one cyclopentyl in the same place.)
References
Butamirate Wikipedia(Text) CC BY-SA