Bustos is a surname. Notable people with the surname include:
Arturo García Bustos, Mexican painter
Cristian Bustos, Spanish football player
Crystl Bustos, Mexican-American softball player
Diego Daniel Bustos, retired Argentine football striker
Eduardo Bustos Montoya, Argentine football striker
David Bustos (born 1990), Spanish athlete
Diego Bustos, Argentine news anchor
H. Bustos Domecq, pseudonym used for several collaborative works by the Argentine writers Jorge Luis Borges and Adolfo Bioy Casares
Isaac Bustos, Mexican boxer
Joey Bustos, drummer and member of the band Link 80
Juan Bustos, Chilean politician
Judith Bustos, better known as Tigresa del Oriente, Peruvian singer
Martin Bustos Moyano, Argentine rugby union player
Maximiliano Bustos, Argentine football midfielder
Mikey Bustos (born 1981), Filipino-Canadian singer
Rubén Darío Bustos, Colombian football player
Sergio Bustos, retired Argentine football player
Ramón Moreno Bustos, Spanish politician
Vanessa Alexandra Mendoza Bustos, better known as Vanessa Mendoza, Colombian fashion model