Burne (variations: Byrnes, Byrne, O'Byrne, O'Byrnes, Burns, Beirne, Bourne) is a surname. Notable people with the surname include:
Alfred Burne (1886–1959), soldier and military historian
Burne Hogarth (1911–1996), American cartoonist, illustrator, educator, author and theoretician
Charlotte Sophia Burne (1850–1923), author and editor, president of the Folklore Society
Christopher F. Burne, Brigadier General in the United States Air Force
Edward Burne-Jones (1833–1898), British artist and designer who worked closely with William Morris
Grayson Burne, British sprint canoeist who competed from the early 1980s to the mid-1990s
James Burne Ferguson, 19th century Member of Parliament in New Zealand
Loh Gwo Burne (born 1974), Malaysian politician
Nancy Burne (1912–1954), British film actress
Nicol Burne (1574–1598), Scottish Roman Catholic controversialist
Philip Burne-Jones (1861–1926), the first child of the British Pre-Raphaelite artist Sir Edward Burne-Jones
