Buescher or Büscher is a German surname. Notable people with the surname include:
Arnold Büscher (1899–1949), German Nazi concentration camp commandant
Bernie Buescher, the current secretary of state in Colorado
Chris Buescher (born 1992), NASCAR driver
Erin Buescher Perperoglou (born 1979), an American basketball player
James Buescher (born 1990), NASCAR driver
Julianne Buescher (born 1965), an American actress
Ulrich Büscher (born 1958), German football player