Brunelle is a surname. Notable people with the surname include:
Francis Brunelle (born 1949), French Neuroradiologist, pediatric radiologist and political figure in FranceHervé-Edgar Brunelle (1891–1950), Canadian politician and lawyerHonoré Brunelle Tourigny (1857–1918), surveyor, engineer and political figure in QuebecLiina Brunelle (born 1978), French-Russian actressLucas Brunelle, videographer for bicycle events and a bicycle advocatePaul Brunelle (1923–1994), singer-songwriter and country guitarist of western QuebecPaule Brunelle (born 1953), Canadian politicianPhilip Brunelle, American conductor, choral scholar and organistPierre Brunelle (born 1991), French engineer and entrepreneurRené Brunelle (1920–2010), Ontario political figure